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HFIP Hexafluoroisopropanol CAS 920-66-1 for Pharmaceutical Synthesis and Polymer Science

Name: HFIP Hexafluoroisopropanol CAS 920-66-1 for Pharmaceutical Synthesis and Polymer Science
Brand: Shenhui (Shanghai) Technology Development Co., Ltd.
SKU: Cas No 920-66-1
Availability: InStock

Brand Name:	HFIP(Hexafluoroisopropanol)
Model Number:	Cas No 920-66-1
MOQ:	1kg
Payment Terms:	L/C,D/A,D/P,T/T
Supply Ability:	1 week

Detail Information

Product Description

Detail Information

Place of Origin:

China

Certification:

Qualified

Cas No:

920-66-1

EINECS:

213-059-4

Density:

1.596 G/mL At 25°C

Melting Point:

-4°C

Storage:

Store Below +30°C

Color:

White To Yellow

Packaging Details:

(PTFE) / PFA bottles（Customizable）

Highlight:

Solvents Hexafluoroisopropanol

Coatings Hexafluoroisopropanol

Pesticides Hexafluoroisopropanol

Product Description

HFIP Hexafluoroisopropanol

CAS No 920-66-1 - For Solvents, Coatings, Medicine, Pesticides, and Chemical Cleaning Applications

Product Overview

HFIP (Hexafluoroisopropanol) is a powerful fluorinated alcohol solvent with exceptional solvating properties. Its unique molecular structure makes it indispensable in pharmaceutical synthesis, peptide chemistry, and polymer processing, earning it the reputation as a "magic solvent" for facilitating chemical reactions.

Key Characteristics & Applications

Strong Polarity & Hydrogen Bond Donor: Effectively dissolves stubborn compounds including peptides and high-performance plastics while stabilizing reaction intermediates through hydrogen bonding
Weak Acidity: Enhanced acidity (pKa ≈ 9.3) compared to typical alcohols, aiding in disrupting biomolecule secondary structures
Low Boiling Point & High Density: Boils at 58-59°C for easy distillation recovery with density of approximately 1.6 g/mL
Pharmaceutical & Peptide Synthesis: High-efficiency dissolving agent that prevents peptide aggregation and serves as critical solvent in Solid-Phase Peptide Synthesis (SPPS)
Polymer Science: Superior solvent for high-performance engineering plastics including PEEK and polyimides, used for thin films, fibers, and coatings
Analytical Chemistry: Optimal matrix solvent in MALDI-MS analysis for achieving clearer, higher-resolution mass spectra of proteins and peptides

Excellent Solubility: Miscible with water and most common organic solvents

Technical Specifications

Parameter	Specification
Chemical Name	Hexafluoroisopropanol
CAS Number	920-66-1
Molecular Formula	C₃H₂F₆O
Boiling Point	58 - 59 °C
Density	1.596 g/mL (25°C)
Purity	≥99% (GC)
Packaging	100ml, 500ml, 1L, 5L, 20L

Packaging & Safety

HFIP is packaged in sealed Teflon (PTFE/PFA) or High-Density Polyethylene (HDPE) bottles to ensure safety and maintain purity. All packaging undergoes leak-testing and includes secondary containment with absorbent materials, complying with hazardous chemical transportation regulations.

Frequently Asked Questions

Q1: What are the main safety hazards of HFIP?

HFIP is corrosive and causes severe skin burns and eye damage. It is also harmful if inhaled. Always handle inside a fume hood with appropriate PPE including gloves, safety goggles, and a lab coat.

Q2: What common plastics does HFIP dissolve?

HFIP is a strong solvent for many plastics, including PEEK, polyamides (nylon), and polycarbonate. Teflon (PTFE) is completely resistant to it.

Q3: How should I store HFIP?

Store in a cool, dry, well-ventilated area. Keep containers tightly closed and away from heat, sparks, and open flames.

Tags:

Plastic Resin

Ethylene Tetrafluoroethylene ETFE

PVDF Polyvinylidene Fluoride

PTFE Polytetrafluoroethylene

PFA

FEP Fluorinated Ethylene Propylene

Fine Chemical

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PMVE

HFP Hexafluoropropylene

HFPO

Octafluorocyclobutane

Perfluoropolyether Carboxylic Acid

AHF Chemical

HFIP Chemical

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Bisphenol AF

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